Metaxalone API Manufacturer & Supplier in India

What is Metaxalone API?

Metaxalone (CAS No. 1665-48-1) is an oxazolidinone-derivative compound formulated as a skeletal muscle relaxant, historically marketed under the brand name Skelaxin. Its precise mechanism of action has not been definitively established in the pharmacological literature — unlike many muscle relaxants, it does not appear to act directly on striated muscle fibres, the neuromuscular junction or motor nerve conduction. Current understanding attributes its clinical effect to general central nervous system depression rather than a peripheral action, which is a meaningful technical distinction for formulators comparing it against other agents in the same category.

Metaxalone is generally used as an adjunct to rest, physical therapy and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions such as strains and sprains. Apex Pharma API manufactures and supplies the API itself — the bulk active ingredient — not the finished branded or generic product.

Metaxalone API manufacturing at Apex Pharma API

We have manufactured Metaxalone in-house since 2015 at our Saykha GIDC plant in Bharuch, on a single established route that keeps the impurity profile steady from campaign to campaign. Production runs in a 4 KL stainless-steel reactor, so we supply from evaluation samples through to repeat commercial volumes, and you buy directly from the plant that makes it with the QC team that released the batch on hand. Our complete product range and general sourcing process are covered on our API manufacturing page.

Applications and uses

Metaxalone API is used in formulations intended to relieve musculoskeletal pain and muscle spasm associated with acute strains and sprains, typically as an adjunct to rest and physical therapy rather than as a standalone intervention. Clinical literature notes a relatively low reported incidence of side effects compared with some other agents in the muscle-relaxant category, which is part of why the molecule maintains steady formulation demand despite a smaller supplier base than more widely produced muscle relaxants. This is general pharmacological context for buyer understanding, not a claim about specific finished products manufactured by our customers.

Industries and customers we serve

Metaxalone API from Apex Pharma API is supplied to pharmaceutical formulation manufacturers producing solid oral dosage forms, to distributors supplying API onward within their own network, and to R&D and generic-development teams needing API for formulation trials ahead of scale-up. Our full buyer-segment breakdown is on the API manufacturing companies in India page.

Why choose Apex Pharma API for Metaxalone API

• GMP- and GLP-certified manufacturing (Gujarat FDCA), with an ISO 9001:2015 quality management system and MSME ZED Bronze certification.
• Manufactured in-house since 2015 on a single established route at our Saykha GIDC plant, so the impurity profile is consistent campaign to campaign.
• A batch-wise Certificate of Analysis as standard, with MSDS, specification sheet and method of analysis available, and DMF documentation on request.
• Manufacturer pricing, quoted directly — supply from trial quantities through to repeat commercial volumes, with evaluation samples available before a bulk order.